Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489974 | 1.00 | HPGD (0.49) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7484765 | 1.00 | HPGD (0.49) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7483826 | 0.87 | CYP4F2 (0.51) | HPGDALDH1A1RAB9ATSHRKMT2A | |
| SCHEMBL7490164 | 0.87 | CYP4F2 (0.51) | HPGDALDH1A1RAB9ATSHRKMT2A | |
| SCHEMBL7483813 | 0.87 | CYP4F2 (0.51) | HPGDALDH1A1RAB9ATSHRKMT2A | |
| SCHEMBL7488184 | 0.82 | CYP4F2 (0.51) | HPGDALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL27719180 | 0.79 | L3MBTL1 (0.46) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL4625575 | 0.78 | HPGD (0.52) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7487013 | 0.76 | MAPT (0.48) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL7485154 | 0.76 | MAPT (0.48) | HPGDALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825189-B1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN PHARMA INC (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6130243-A | PROPHYLACTIC OR THERAPEUTIC AGENT FOR DIABETES, HYPERGLYCEMIA AND OBESITY IN MAMMALS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| EP-0825189-A1 | 1,4-BENZODIOXIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |