Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202581 | 0.80 | NPC1 (0.56) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL1987865 | 0.80 | TAAR1 (0.52) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL27862778 | 0.79 | NPC1 (0.51) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL1985442 | 0.79 | NPC1 (0.51) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL3486501 | 0.79 | NPC1 (0.51) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL4788685 | 0.78 | NPC1 (0.55) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL5690104 | 0.76 | NPC1 (0.49) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL18389133 | 0.76 | NPC1 (0.45) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL18389132 | 0.76 | NPC1 (0.45) | NPC1ADAM17KDM4EMAPTMAPK1 | |
| SCHEMBL1317999 | 0.76 | NPC1 (0.45) | NPC1ADAM17KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221385-B | Aryl diazonium salts and use in electrolyte solutions of electrochemical generators | COMMISSARIAT ENERGIE ATOMIQUE | 2015-06-03 | — | — | CN | disclosed |
| CN-103221385-A | Aryl diazonium salts and use in electrolyte solutions of electrochemical generators | COMMISSARIAT ENERGIE ATOMIQUE | 2013-07-24 | — | — | CN | disclosed |
| EP-0072352-A1 | Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and the compounds for therapeutical use | CIBA-GEIGY AG (CH) | 1983-02-16 | — | — | EP | disclosed |
| US-4213920-A | Process for the production of substituted benzaldehydes | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |