Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CPA1 | P15085 | 3/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862778 | 1.00 | NPC1 (0.51) | NPC1ADAM17TAAR1TRPA1MEN1 | |
| SCHEMBL1985442 | 1.00 | NPC1 (0.51) | NPC1ADAM17TAAR1TRPA1MEN1 | |
| SCHEMBL1984032 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL17466741 | 0.82 | ALDH1A1 (0.50) | MEN1KMT2AKDM4EMAPTMAPK1 | |
| SCHEMBL9202581 | 0.80 | NPC1 (0.56) | NPC1ADAM17MEN1POLBKMT2A | |
| SCHEMBL17466748 | 0.80 | ALDH1A1 (0.49) | MEN1POLBKMT2AKDM4EMAPT | |
| SCHEMBL1987865 | 0.80 | TAAR1 (0.52) | NPC1ADAM17TAAR1MEN1POLB | |
| SCHEMBL1983437 | 0.80 | ALDH1A1 (0.49) | MEN1POLBKMT2AKDM4EMAPT | |
| SCHEMBL5690104 | 0.80 | NPC1 (0.49) | NPC1ADAM17MEN1POLBKMT2A | |
| SCHEMBL8586940 | 0.80 | ALDH1A1 (0.43) | NPC1ADAM17MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |
| US-9744528-B2 | Metallorganocatalysis for asymmetric transformations | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160023198-A1 | Metallorganocatalysis For Asymmetric Transformations | Rutgars, The State University of New Jersey (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160023198-A1 | Metallorganocatalysis For Asymmetric Transformations | Rutgars, The State University of New Jersey (US) | 2016-01-28 | — | — | US | disclosed |
| US-8313923-B2 | Process for enzymatic reduction of alkene derivatives | BASF SE (DE) | 2012-11-20 | — | — | US | disclosed |
| US-20100035315-A1 | Any alpha-beta unsaturated ketone, aldehyde, carboxy or ester, or vinyl-unsaturated nitro compound to corresponding saturated compound; for example, citral to citronellal or 3-methylcyclohexenone to 3-methylcyclohexanone, using biocatalyst; stereospecific and efficient | BASF SE (DE) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160023198-A1 | Metallorganocatalysis For Asymmetric Transformations | SOD1, AOC3, CBR1 | NPC1 3226/4885ADAM17 4494/4885TAAR1 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.