Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.72 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.72 |
| ▸ | ITGAV | P06756 | 7/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7495244 | 0.95 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL7486656 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BITGAV | |
| SCHEMBL7037924 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL7490874 | 0.86 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL8460133 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BITGAV | |
| SCHEMBL7490912 | 0.85 | ITGB3 (0.91) | ITGB3ITGA2BITGAV | |
| SCHEMBL7037266 | 0.84 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7487559 | 0.83 | ITGB3 (0.76) | ITGB3ITGA2BITGAV | |
| SCHEMBL244700 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL6649836 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760658-B1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | claimed |
| EP-0760658-B1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | disclosed |