Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 7/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.36 |
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486288 | 0.98 | F2 (0.38) | F2F10PRSS1TMPRSS15SPHK1 | |
| SCHEMBL7492363 | 0.92 | KDM4E (0.41) | F2F10PRSS1 | |
| SCHEMBL7490136 | 0.90 | ALDH1A1 (0.39) | F2F10PRSS1TMPRSS15SPHK1 | |
| SCHEMBL7495849 | 0.89 | F2 (0.37) | F2F10PRSS1TMPRSS15ITGB3 | |
| SCHEMBL7484602 | 0.89 | F2 (0.37) | F2F10PRSS1TMPRSS15ITGB3 | |
| SCHEMBL7491298 | 0.87 | F2 (0.38) | F2F10PRSS1TMPRSS15ITGB3 | |
| SCHEMBL7485043 | 0.86 | F2 (0.37) | F2F10PRSS1TMPRSS15SPHK1 | |
| SCHEMBL7487357 | 0.85 | F2 (0.36) | F2F10PRSS1TMPRSS15SPHK1 | |
| SCHEMBL7492740 | 0.85 | F2 (0.38) | F2F10PRSS1TMPRSS15SPHK1 | |
| SCHEMBL7447646 | 0.85 | F2 (0.39) | F2F10PRSS1TMPRSS15ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |