Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 12/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566760 | 0.88 | PTGER1 (0.47) | PTGER1TBXA2RBRD4MAPTMAPK1 | |
| SCHEMBL6604823 | 0.86 | PTGS1 (0.55) | PTGER1TBXA2R | |
| SCHEMBL6603715 | 0.84 | PTGER1 (0.48) | PTGER1TBXA2RBRD4L3MBTL1 | |
| SCHEMBL6605630 | 0.84 | PTGER1 (0.48) | PTGER1TBXA2RBRD4 | |
| SCHEMBL6604669 | 0.84 | RXRA (0.62) | PTGER1TBXA2RHPGD | |
| SCHEMBL6604924 | 0.83 | PTGER1 (0.62) | PTGER1TBXA2R | |
| SCHEMBL10093045 | 0.81 | SYK (0.63) | PTGER1BRD4MAOBALDH1A1MAPT | |
| SCHEMBL26013299 | 0.74 | MAPT (0.63) | PTGER1BRD4MAPTMAPK1TDP1 | |
| SCHEMBL6605970 | 0.73 | RXRA (0.66) | PTGER1TBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL13114653 | 0.72 | MAPT (0.53) | BRD4MAOBMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216238-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck Frosst Canada & Co. (CA) | 2002-06-26 | — | — | EP | claimed |
| WO-2001019814-A2 | CARBOXYLIC ACIDS AND ACYLSULFONAMIDES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK FROSST CANADA & CO. (CA) | 2001-03-22 | — | — | WO | claimed |