SCHEMBL7489299

SCHEMBL7489299

CCCC(=O)OCCc1nccc(N2C[C@@H](C)N(c3ccnc(CCOC(=O)CCC)n3)[C@@H](C)C2)n1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SORD Q00796 17/20 0.53
ACACB O00763 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294419 0.92 SORD (0.68) SORD
SCHEMBL7489010 0.92 SORD (0.68) SORD
SCHEMBL6293367 0.92 SORD (0.68) SORD
SCHEMBL6294479 0.92 SORD (0.46) SORDACACB
SCHEMBL6297961 0.90 SORD (0.52) SORD
SCHEMBL6294420 0.90 SORD (0.56) SORD
SCHEMBL6294405 0.90 SORD (0.56) SORD
SCHEMBL6293078 0.90 SORD (0.55) SORD
SCHEMBL6298935 0.89 SORD (0.43) SORDACACB
SCHEMBL6293393 0.89 SORD (0.42) SORDACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1185275-A1 AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS Pfizer Products Inc. (US) 2002-03-13 EP claimed
WO-2000059510-A1 AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS PFIZER PRODUCTS INC. (US) 2000-10-12 WO claimed
EP-1185275-A1 AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS Pfizer Products Inc. (US) 2002-03-13 EP disclosed
WO-2000059510-A1 AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS PFIZER PRODUCTS INC. (US) 2000-10-12 WO disclosed