Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 16/20 | 0.51 |
| ▸ | PPARA | Q07869 | 14/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489328 | 1.00 | FFAR1 (0.53) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL6967143 | 0.89 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6967147 | 0.89 | PPARG (0.67) | PPARGPPARAPPARD | |
| SCHEMBL6966729 | 0.85 | FFAR1 (0.61) | FFAR1KDM4EPPARGPPARA | |
| SCHEMBL6966725 | 0.85 | FFAR1 (0.61) | FFAR1KDM4EPPARGPPARA | |
| SCHEMBL7481879 | 0.83 | KDM4E (0.52) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL7481872 | 0.83 | KDM4E (0.52) | FFAR1KDM4EPPARGPPARAPPARD | |
| SCHEMBL8888613 | 0.81 | FDPS (0.64) | KDM4EPPARGPPARAPPARD | |
| SCHEMBL8888616 | 0.81 | FDPS (0.64) | KDM4EPPARGPPARAPPARD | |
| SCHEMBL7486865 | 0.81 | PPARG (0.53) | FFAR1KDM4EPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643050-B1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-04-10 | — | — | EP | disclosed |
| US-5614544-A | HYPOGLYCEMIC AND HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0643050-A1 | Oxazolidinedione derivatives and their use as hypoglycemic agent | Takeda Chemical Industries, Ltd. (JP) | 1995-03-15 | — | — | EP | disclosed |