Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214597 | 0.86 | SLC6A4 (0.57) | SLC6A4HTR1ADRD2MEN1HTT | |
| SCHEMBL30557975 | 0.81 | PTGER1 (0.54) | SLC6A4PTGER1 | |
| Picolamine SCHEMBL29071785 | 0.79 | MEN1 (0.53) | SLC6A4HTR1ADRD2MEN1HTT | |
| SCHEMBL31252511 | 0.79 | MEN1 (0.75) | MEN1HTTKMT2APTGER1LRRK2 | |
| SCHEMBL6216769 | 0.78 | GRM5 (0.54) | SLC6A4HTR1ADRD2MEN1HTT | |
| SCHEMBL30335622 | 0.77 | SLC6A4 (0.56) | SLC6A4HTR1ADRD2MEN1HTT | |
| SCHEMBL14008090 | 0.75 | PTGER1 (0.66) | MEN1KMT2APTGER1LRRK2POLB | |
| SCHEMBL4924916 | 0.74 | PTGER1 (0.77) | MEN1KMT2APTGER1 | |
| SCHEMBL8881389 | 0.73 | HTT (0.62) | SLC6A4MEN1HTTKMT2AALDH1A1 | |
| SCHEMBL2283761 | 0.73 | SLC6A4 (1.00) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216257-A1 | COMPOUNDS FOR THE TREATMENT OF ISCHEMIA | Pfizer Products Inc. (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001023399-A1 | COMPOUNDS FOR THE TREATMENT OF ISCHEMIA | PFIZER PRODUCTS INC. (US) | 2001-04-05 | — | — | WO | disclosed |