Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214597 | 0.91 | SLC6A4 (0.57) | MEN1HTTKMT2APTGER1LRRK2 | |
| Ammonia Solution, Strong SCHEMBL29071779 | 0.88 | MRGPRX4 (0.53) | HTTPTGER1CCR5SLC6A4ALDH1A1 | |
| SCHEMBL1196687 | 0.86 | CCR5 (0.64) | KMT2APTGER1CCR5SLC6A4MRGPRX4 | |
| Hydrochloric Acid SCHEMBL6214742 | 0.85 | CCR5 (0.62) | KMT2APTGER1CCR5SLC6A4MRGPRX4 | |
| SCHEMBL31252511 | 0.81 | MEN1 (0.75) | MEN1HTTKMT2APTGER1LRRK2 | |
| SCHEMBL7489582 | 0.79 | SLC6A4 (0.57) | MEN1HTTKMT2APTGER1LRRK2 | |
| Hydrochloric Acid SCHEMBL6215773 | 0.76 | CCR5 (0.75) | PTGER1CCR5SLC6A4MRGPRX4STAT3 | |
| Hydrochloric Acid SCHEMBL6213322 | 0.75 | MRGPRX4 (0.62) | CCR5SLC6A4MRGPRX4 | |
| SCHEMBL4720836 | 0.73 | PTGER1 (0.56) | PTGER1CCR5SLC6A4STAT3 | |
| SCHEMBL6216769 | 0.73 | GRM5 (0.54) | MEN1HTTKMT2APTGER1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116687925-A | Aggressive protease inhibitor and application thereof | 中国科学院遗传与发育生物学研究所 | 2023-09-05 | — | — | CN | disclosed |