Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946657 | 0.70 | GABRR1 (0.34) | — | |
| SCHEMBL2412348 | 0.63 | CYP2C19 (0.52) | CYP2C9CYP2C19 | |
| SCHEMBL5072477 | 0.63 | GGT1 (0.38) | GGT1 | |
| SCHEMBL27203661 | 0.63 | GABRR1 (0.33) | — | |
| SCHEMBL27207370 | 0.63 | GABRR1 (0.33) | — | |
| SCHEMBL2773704 | 0.62 | — | — | |
| Acetic Acid SCHEMBL28069700 | 0.62 | GGT1 (0.41) | GGT1 | |
| SCHEMBL26452831 | 0.62 | — | — | |
| SCHEMBL11306525 | 0.62 | GGT1 (0.37) | GGT1 | |
| SCHEMBL15231954 | 0.62 | CYP2C19 (0.50) | CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218384-A4 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| EP-1218384-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023392-A1 | TETRACYCLIC BENZIMIDAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2001-04-05 | — | — | WO | disclosed |