Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.41 |
| ▸ | KDM5A | P29375 | 5/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.38 |
| ▸ | ADH1A | P07327 | 2/20 | 0.38 |
| ▸ | ADH4 | P08319 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199544 | 1.00 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL5542815 | 0.92 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL5540488 | 0.92 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL5542153 | 0.84 | S1PR2 (0.36) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL11756349 | 0.80 | ADH1C (0.36) | DNM1KDM5AKDM4CPHF8ADH1C | |
| SCHEMBL2171824 | 0.79 | KCNH2 (0.41) | DNM1KDM5AKDM4CADH1CADH1A | |
| SCHEMBL5540536 | 0.78 | ADH1C (0.39) | DNM1KDM5AKDM4CPHF8ADH1C | |
| Formic Acid SCHEMBL28426676 | 0.77 | S1PR2 (0.59) | S1PR2S1PR1S1PR3S1PR5DNM1 | |
| SCHEMBL93202 | 0.77 | TSHR (0.46) | ADH1CADH1AADH4EPHX1ADH1B | |
| SCHEMBL2857805 | 0.77 | TSHR (0.46) | ADH1CADH1AADH4EPHX1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261731-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | Urtti, Arto (FI) | 2002-12-04 | — | — | EP | claimed |
| WO-2001062946-A1 | CATIONIC AMPHIPHILIC 1,4-DIHYDROPYRIDINE DERIVATIVES USEFUL FOR DELIVERY OF NUCLEOTIDE CONTAINING COMPOUNDS | URTTI ARTO (FI) | 2001-08-30 | — | — | WO | claimed |