Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491799 | 1.00 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7492498 | 0.89 | CHRM3 (0.37) | CCR5CHRM3HCRTR1HCRTR2 | |
| SCHEMBL7492513 | 0.89 | CHRM3 (0.37) | CCR5CHRM3HCRTR1HCRTR2 | |
| SCHEMBL7492507 | 0.89 | CHRM3 (0.37) | CCR5CHRM3HCRTR1HCRTR2 | |
| SCHEMBL7958035 | 0.86 | EP300 (0.34) | DPP4DPP8CCR5CHRM3TACR1 | |
| SCHEMBL7958028 | 0.86 | EP300 (0.34) | DPP4DPP8CCR5CHRM3TACR1 | |
| SCHEMBL7953676 | 0.85 | HRH3 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7953672 | 0.85 | HRH3 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7953675 | 0.85 | HRH3 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL7491392 | 0.84 | SLC6A4 (0.42) | HRH3ACSS2KCNH2HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |