Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.37 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492498 | 1.00 | CHRM3 (0.37) | CHRM3CCR5AGTR2HCRTR1HCRTR2 | |
| SCHEMBL7492513 | 1.00 | CHRM3 (0.37) | CHRM3CCR5AGTR2HCRTR1HCRTR2 | |
| SCHEMBL7491799 | 0.89 | DPP4 (0.41) | CHRM3CCR5HCRTR1HCRTR2 | |
| SCHEMBL7489797 | 0.89 | DPP4 (0.41) | CHRM3CCR5HCRTR1HCRTR2 | |
| SCHEMBL7491392 | 0.85 | SLC6A4 (0.42) | HCRTR1HCRTR2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL7958035 | 0.85 | EP300 (0.34) | CHRM3CCR5HCRTR1HCRTR2ROCK2 | |
| SCHEMBL7958028 | 0.85 | EP300 (0.34) | CHRM3CCR5HCRTR1HCRTR2ROCK2 | |
| SCHEMBL7953672 | 0.85 | HRH3 (0.36) | CHRM3HCRTR1HCRTR2SLC6A4KDM4E | |
| SCHEMBL7953676 | 0.85 | HRH3 (0.36) | CHRM3HCRTR1HCRTR2SLC6A4KDM4E | |
| SCHEMBL7953675 | 0.85 | HRH3 (0.36) | CHRM3HCRTR1HCRTR2SLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |