Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309509 | 1.00 | ADORA1 (0.47) | ADORA1USP30EGFRSRCBTK | |
| SCHEMBL7490416 | 0.95 | ADORA1 (0.48) | ADORA1USP30EGFRSRCSPR | |
| SCHEMBL7661798 | 0.90 | ADORA1 (0.45) | ADORA1USP30SPR | |
| SCHEMBL9035991 | 0.90 | ADORA1 (0.45) | ADORA1USP30SPR | |
| SCHEMBL7664140 | 0.88 | ADORA1 (0.46) | ADORA1USP30SPR | |
| SCHEMBL7655503 | 0.87 | ADORA1 (0.45) | ADORA1USP30SPR | |
| SCHEMBL7487132 | 0.84 | ADORA1 (0.52) | ADORA1 | |
| SCHEMBL7487498 | 0.80 | ADORA1 (0.53) | ADORA1EGFRBTK | |
| Hydrochloric Acid SCHEMBL7541956 | 0.79 | ADORA1 (0.52) | ADORA1EGFRBTK | |
| SCHEMBL7494888 | 0.79 | ADORA1 (0.50) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925299-B1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6124456-A | Pyrazolopyridine compound and pharmaceutical use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0925299-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998003507-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |