Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664140 | 0.88 | ADORA1 (0.46) | ADORA1SPRMAPK1CKS1BSKP1 | |
| SCHEMBL7490072 | 0.87 | ADORA1 (0.47) | ADORA1SPRUSP30 | |
| SCHEMBL8309509 | 0.87 | ADORA1 (0.47) | ADORA1SPRUSP30 | |
| SCHEMBL7490416 | 0.85 | ADORA1 (0.48) | ADORA1SPRMAPK1CKS1BSKP1 | |
| SCHEMBL9035991 | 0.85 | ADORA1 (0.45) | ADORA1SPRUSP30 | |
| SCHEMBL7661798 | 0.85 | ADORA1 (0.45) | ADORA1SPRUSP30 | |
| SCHEMBL7662071 | 0.80 | ADORA1 (0.52) | ADORA1MAPK1IGF1R | |
| SCHEMBL7654955 | 0.79 | ADORA1 (0.51) | ADORA1MAPK1IGF1R | |
| SCHEMBL7659038 | 0.78 | ADORA1 (0.45) | ADORA1MAPK1IGF1R | |
| SCHEMBL7659044 | 0.78 | ADORA1 (0.45) | ADORA1MAPK1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-0737193-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018128-A1 | PYRAZOLOPYRIDINE ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-06 | — | — | WO | disclosed |