Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | MGLL | Q99685 | 3/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481753 | 1.00 | PTGS1 (0.52) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL7482405 | 1.00 | PTGS1 (0.52) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL7487859 | 0.92 | SMN1; SMN2 (0.50) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL22845022 | 0.87 | EPHX2 (0.44) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL7453826 | 0.83 | KMT2A (0.53) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL13291898 | 0.82 | SMN1; SMN2 (0.46) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL11845960 | 0.82 | CNR2 (0.46) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL25473085 | 0.82 | CNR2 (0.39) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL11860195 | 0.81 | ALDH1A1 (0.50) | PTGS1PTGS2MGLLFAAHCNR2 | |
| SCHEMBL13606475 | 0.81 | SMN1; SMN2 (0.45) | PTGS1PTGS2MGLLFAAHCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929522-B1 | INSECT-REPELLENT FORMULATIONS | PFIZER LTD (GB) | 2002-12-18 | — | — | EP | disclosed |
| US-6130241-A | Insect-repellent formulations | PFIZER INC. (US) | 2000-10-10 | — | — | US | disclosed |
| EP-0929522-A1 | INSECT-REPELLENT FORMULATIONS | Pfizer Limited (GB) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013345-A1 | INSECT-REPELLENT FORMULATIONS | PFIZER LIMITED (GB) | 1998-04-02 | — | — | WO | disclosed |