Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 15/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299092 | 1.00 | SORD (0.36) | SORDACACBEIF2AK4 | |
| SCHEMBL7493434 | 0.86 | SORD (0.45) | SORDACACB | |
| SCHEMBL6293077 | 0.86 | SORD (0.45) | SORDACACB | |
| SCHEMBL7492661 | 0.81 | SORD (0.34) | SORDACACB | |
| SCHEMBL6293140 | 0.81 | SORD (0.34) | SORDACACB | |
| SCHEMBL6298854 | 0.80 | SORD (0.42) | SORD | |
| SCHEMBL7499515 | 0.80 | SORD (0.42) | SORD | |
| SCHEMBL6294682 | 0.76 | SORD (0.46) | SORD | |
| SCHEMBL7566231 | 0.76 | SORD (0.46) | SORD | |
| SCHEMBL6297967 | 0.76 | SORD (0.34) | SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185275-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | Pfizer Products Inc. (US) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000059510-A1 | AMINOPYRIMIDINES AS SORBITOL DEHYDROGENASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2000-10-12 | — | — | WO | disclosed |