Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489848 | 1.00 | SLC6A4 (0.48) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7491564 | 0.97 | SLC6A4 (0.49) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7452507 | 0.97 | SLC6A4 (0.49) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7491888 | 0.92 | SLC6A4 (0.38) | SLC6A4HRH3DRD2DRD3SLC6A2 | |
| SCHEMBL7491878 | 0.92 | SLC6A4 (0.38) | SLC6A4HRH3DRD2DRD3SLC6A2 | |
| SCHEMBL7487244 | 0.91 | SLC6A4 (0.48) | SLC6A4HRH3DRD2DRD3SLC6A2 | |
| SCHEMBL7487240 | 0.91 | SLC6A4 (0.48) | SLC6A4HRH3DRD2DRD3SLC6A2 | |
| SCHEMBL7496632 | 0.86 | SLC6A4 (0.50) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7496636 | 0.86 | SLC6A4 (0.50) | SLC6A4CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7490900 | 0.83 | HRH3 (0.33) | SLC6A4HRH3SLC6A2SLC6A3ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |