Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491377 | 0.88 | CYP11B2 (0.34) | HRH3ACSS2CYP11B2CYP11B1CCR9 | |
| SCHEMBL7491888 | 0.85 | SLC6A4 (0.38) | HRH3ACSS2CYP11B2CYP11B1CCR9 | |
| SCHEMBL7491878 | 0.85 | SLC6A4 (0.38) | HRH3ACSS2CYP11B2CYP11B1CCR9 | |
| SCHEMBL7490721 | 0.83 | SLC6A4 (0.48) | HRH3ACSS2CYP11B2SLC6A4SLC6A2 | |
| SCHEMBL7489848 | 0.83 | SLC6A4 (0.48) | HRH3ACSS2CYP11B2SLC6A4SLC6A2 | |
| SCHEMBL7452507 | 0.82 | SLC6A4 (0.49) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7491564 | 0.82 | SLC6A4 (0.49) | HRH3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27401589 | 0.76 | PPARG (0.43) | HRH3ACSS2CYP11B2CYP11B1CCR9 | |
| SCHEMBL7485835 | 0.75 | ALDH1A1 (0.38) | ACSS2CYP11B2CYP11B1CCR9CACNA2D1 | |
| SCHEMBL7485833 | 0.75 | ALDH1A1 (0.38) | ACSS2CYP11B2CYP11B1CCR9CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |