Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962938 | 0.83 | C1S (0.54) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL992992 | 0.81 | C1S (0.52) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL28062914 | 0.81 | C1S (0.52) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL3178752 | 0.81 | C1S (0.63) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL29364384 | 0.81 | C1S (0.52) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL28879914 | 0.81 | C1S (0.52) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL30277354 | 0.81 | PARP1 (0.63) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL3169 | 0.81 | PARP1 (0.63) | C1SPARP1L3MBTL1ALDH1A1TP53 | |
| SCHEMBL1551882 | 0.81 | FURIN (0.46) | PARP1L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL16955875 | 0.79 | C1S (0.50) | C1SPARP1L3MBTL1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103254221-B | Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo [1,2-a ] pyridine and process for their preparation | SANOFI AVENTIS | 2014-11-19 | — | — | CN | disclosed |
| CN-102036987-B | Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo [1,2-a ] pyridines, process for their preparation and their therapeutic use | SANOFI AVENTIS | 2014-01-01 | — | — | CN | disclosed |
| CN-103254221-A | Polysubstituted derivatives of 2-heteroaryl-6-phenylimidazo [1,2-a ] pyridines, process for their preparation and their therapeutic use | SANOFI AVENTIS | 2013-08-21 | — | — | CN | disclosed |
| CN-102458123-A | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof | ALBANY MOLECULAR RES INC | 2012-05-16 | — | — | CN | disclosed |
| EP-2429295-A1 | ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF | Albany Molecular Research, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132437-A1 | ARYL, HETEROARYL, AND HETEROCYCLE SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-11-18 | — | — | WO | disclosed |
| CN-1694870-A | Acetyl 2-hydroxy-1, 3-diaminoalkanes | PHARMACIA & UPJOHN CO LLC (US) | 2005-11-09 | — | — | CN | disclosed |
| US-5965613-A | FUNGICIDES FOR USE IN AGRICULTURE AND HORTICULTURE; THE COMPOUNDS ALSO HAVE INSECTICIDAL AND ACARICIDAL ACTIVITY | NOVARTIS FINANCE CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | C1S 2634/4885PARP1 1166/4885L3MBTL1 3787/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | C1S 2634/4885PARP1 1166/4885L3MBTL1 3787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.