Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491308 | 1.00 | SLC6A4 (0.50) | SLC6A4HRH3RORCPSEN1PSEN2 | |
| SCHEMBL7496636 | 0.91 | SLC6A4 (0.50) | SLC6A4HRH3RORCKDM1ACYP1A2 | |
| SCHEMBL7496632 | 0.91 | SLC6A4 (0.50) | SLC6A4HRH3RORCKDM1ACYP1A2 | |
| SCHEMBL7487240 | 0.86 | SLC6A4 (0.48) | SLC6A4HRH3KDM1ANOS1 | |
| SCHEMBL7487244 | 0.86 | SLC6A4 (0.48) | SLC6A4HRH3KDM1ANOS1 | |
| SCHEMBL7490721 | 0.80 | SLC6A4 (0.48) | SLC6A4HRH3KDM1ACYP1A2CYP3A4 | |
| SCHEMBL7489848 | 0.80 | SLC6A4 (0.48) | SLC6A4HRH3KDM1ACYP1A2CYP3A4 | |
| SCHEMBL7487691 | 0.77 | DPP4 (0.43) | SLC6A4HRH3RORC | |
| SCHEMBL7487699 | 0.77 | DPP4 (0.43) | SLC6A4HRH3RORC | |
| SCHEMBL7491564 | 0.76 | SLC6A4 (0.49) | SLC6A4HRH3CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |