Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330736 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5142204 | 0.85 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL6259699 | 0.83 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7490790 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7572803 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7569123 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5146768 | 0.75 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7490617 | 0.74 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8447043 | 0.74 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL7566413 | 0.73 | PTGS2 (0.70) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904269-B1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-01-23 | — | — | EP | disclosed |
| US-6057319-A | CYCLOOXYGENASE-2 INHIBITORS; NON-STEROIDAL ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2000-05-02 | — | — | US | disclosed |
| US-5698584-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1997-12-16 | — | — | US | disclosed |