Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 5/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273775 | 0.93 | TRHR (0.46) | TRHRACE | |
| SCHEMBL7430887 | 0.92 | TRHR (0.51) | TRHR | |
| SCHEMBL7279805 | 0.90 | TRHR (0.46) | TRHRACE | |
| SCHEMBL7433342 | 0.90 | TRHR (0.52) | TRHR | |
| SCHEMBL7428235 | 0.88 | TRHR (0.53) | TRHR | |
| SCHEMBL7430455 | 0.87 | TRHR (0.51) | TRHR | |
| SCHEMBL7432186 | 0.86 | TRHR (0.51) | TRHR | |
| SCHEMBL7283290 | 0.85 | TRHR (0.45) | TRHRACE | |
| SCHEMBL7272927 | 0.84 | TRHR (0.48) | TRHR | |
| SCHEMBL7429579 | 0.82 | TRHR (0.58) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0473993-A2 | Novel peptide derivatives and their pharmaceutical use | Japan Tobacco Inc. (JP) | 1992-03-11 | — | — | EP | disclosed |