Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.69 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.64 |
| ▸ | ITGA5 | P08648 | 8/20 | 0.64 |
| ▸ | ITGAV | P06756 | 4/20 | 0.59 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494247 | 1.00 | ITGB3 (0.69) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| Hydrochloric Acid SCHEMBL7482009 | 0.99 | ITGB3 (0.67) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| Hydrochloric Acid SCHEMBL7482028 | 0.99 | ITGB3 (0.67) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL7490295 | 0.91 | GAA (0.60) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL7490286 | 0.91 | GAA (0.60) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL14270723 | 0.87 | ITGB1 (0.78) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL23668041 | 0.83 | ITGB1 (0.77) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL7490266 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL7490276 | 0.82 | ITGB3 (0.59) | ITGB3ITGA2BITGB1ITGA5ITGAV | |
| SCHEMBL18067793 | 0.81 | ITGB3 (0.72) | ITGB3ITGA2BITGB1ITGA5ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760658-B1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | claimed |