Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6523809 | 0.83 | TSHR (0.67) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL6517417 | 0.82 | TSHR (0.64) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL6513018 | 0.82 | TSHR (0.64) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL6517426 | 0.82 | TSHR (0.64) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| Zinc Ion SCHEMBL6513024 | 0.82 | TSHR (0.64) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL6517423 | 0.82 | TSHR (0.64) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL294724 | 0.80 | TSHR (1.00) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL557939 | 0.78 | TSHR (0.72) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| M-Xylene SCHEMBL28888661 | 0.77 | TDP1 (0.52) | TSHRCYP3A4GPR35ACHEHSD17B10 | |
| SCHEMBL3074528 | 0.77 | GPR35 (0.59) | TSHRCYP3A4GPR35HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101265224-B | Method for preparing 4-trifluoromethylmercaptoaniline | JINTAN LINGYUN CHEMICAL FACTORY | 2010-12-08 | — | — | CN | disclosed |
| EP-1224169-A2 | PRODUCTION OF 5-SUBSTITUTED INDOLINONES AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001027080-A2 | 5-SUBSTITUTED INDOLINONES AND USE THEREOF AS KINASE AND CYCLIN/CDK COMPLEX INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-04-19 | — | — | WO | disclosed |
| EP-0039312-B1 | COLOUR PHOTOPGRAPHIC MATERIAL FOR THE SILVER-DYE BLEACHING PROCESS, PROCESS FOR THE PRODUCTION OF THIS MATERIAL AND ITS USE IN THE PRODUCTION OF PHOTOGRAPHIC IMAGES | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| US-4379819-A | OIL SOLUBLE MONOAZO DYE | CIBA-GEIGY AG (CH) | 1983-04-12 | — | — | US | disclosed |
| EP-0039312-A1 | Colour photopgraphic material for the silver-dye bleaching process, process for the production of this material and its use in the production of photographic images | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |