Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289051 | 0.87 | USP2 (0.44) | USP2SMN1; SMN2MAPK1NR1H2MAPT | |
| SCHEMBL2392691 | 0.87 | USP2 (0.44) | USP2SMN1; SMN2MAPK1NR1H2MAPT | |
| SCHEMBL5599503 | 0.83 | ITGB2 (0.36) | SMN1; SMN2MAPT | |
| SCHEMBL28451158 | 0.83 | ITGB2 (0.36) | SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL28060468 | 0.82 | ITGB2 (0.35) | SMN1; SMN2MAPT | |
| SCHEMBL19617775 | 0.82 | MAPT (0.33) | MAPT | |
| SCHEMBL28286923 | 0.81 | HRH3 (0.33) | HRH3USP2SMN1; SMN2 | |
| SCHEMBL28114989 | 0.81 | HRH3 (0.33) | HRH3USP2SMN1; SMN2 | |
| SCHEMBL3306996 | 0.79 | MAPT (0.39) | MAPT | |
| SCHEMBL7379626 | 0.79 | MAPK1 (0.36) | HRH3MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |