Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28286923 | 1.00 | HRH3 (0.33) | HRH3DPP4USP2SMN1; SMN2CTSK | |
| Pyridine SCHEMBL28077335 | 0.88 | GPR119 (0.32) | — | |
| SCHEMBL749504 | 0.81 | HRH3 (0.35) | HRH3USP2SMN1; SMN2 | |
| SCHEMBL2392691 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2 | |
| SCHEMBL30289051 | 0.81 | USP2 (0.44) | USP2SMN1; SMN2 | |
| SCHEMBL7379626 | 0.79 | MAPK1 (0.36) | HRH3DPP4 | |
| SCHEMBL7359958 | 0.79 | MAPK1 (0.36) | HRH3DPP4 | |
| SCHEMBL22152561 | 0.79 | MAPK1 (0.36) | HRH3DPP4 | |
| SCHEMBL28044432 | 0.78 | HRH3 (0.31) | HRH3 | |
| SCHEMBL25189970 | 0.76 | CCR2 (0.34) | HRH3DPP4CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117150-A | The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino piperazine | 无锡乾浩生物医药有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-111650288-B | Method for detecting (R) -3-tert-butoxycarbonyl aminopiperidine enantiomer | 江苏艾立康医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-109705121-A | A kind of preparation method of Li Gelieting intermediate | 深圳市第二人民医院 | 2019-05-03 | — | — | CN | disclosed |
| CN-106117150-A | The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino piperazine | 无锡乾浩生物医药有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106117150-A | The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino piperazine | 无锡乾浩生物医药有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106117150-A | The synthetic method of medicine intermediate trans 3-t-butoxycarbonyl amino piperazine | 无锡乾浩生物医药有限公司 | 2016-11-16 | — | — | CN | disclosed |