SCHEMBL7495221

SCHEMBL7495221

Cc1nc2cnccc2n1Cc1ccc(C(=O)c2cn(C(=O)N(C)C)c3cccc(C#C[Si](C)(C)C)c23)cc1F

nearest known ligand 0.83

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7496969 0.91 PTAFR (1.00) PTAFR
Hydrochloric Acid SCHEMBL29766888 0.90 PTAFR (0.99) PTAFR
Hydrochloric Acid SCHEMBL7943577 0.90 PTAFR (0.99) PTAFR
SCHEMBL7492823 0.88
SCHEMBL7497573 0.87 PTAFR (0.78) PTAFR
SCHEMBL7501906 0.87 PTAFR (0.80) PTAFR
SCHEMBL7491319 0.84 PTAFR (0.76) PTAFR
SCHEMBL7497571 0.80
SCHEMBL7494053 0.78 PTAFR (0.78) PTAFR
SCHEMBL7503250 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0734386-B1 PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES ABBOTT LAB (US) 2002-02-06 EP disclosed