Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497573 | 0.89 | PTAFR (0.78) | PTAFR | |
| SCHEMBL7496969 | 0.89 | PTAFR (1.00) | PTAFR | |
| Hydrochloric Acid SCHEMBL7943577 | 0.88 | PTAFR (0.99) | PTAFR | |
| SCHEMBL7491319 | 0.88 | PTAFR (0.76) | PTAFR | |
| Hydrochloric Acid SCHEMBL29766888 | 0.88 | PTAFR (0.99) | PTAFR | |
| SCHEMBL7492425 | 0.87 | — | — | |
| SCHEMBL7495221 | 0.87 | PTAFR (0.83) | PTAFR | |
| SCHEMBL7497571 | 0.83 | — | — | |
| SCHEMBL7496109 | 0.81 | PTAFR (0.56) | PTAFR | |
| SCHEMBL7493565 | 0.80 | PTAFR (0.65) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |