Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.67 |
| ▸ | ITGAV | P06756 | 13/20 | 0.67 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.67 |
| ▸ | ITGB1 | P05556 | 6/20 | 0.67 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495242 | 1.00 | ITGB3 (0.67) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7498949 | 0.87 | ITGB3 (0.69) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7498952 | 0.87 | ITGB3 (0.69) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7495439 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7495445 | 0.80 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL23455576 | 0.78 | KMT2A (0.54) | HPGDMAPTKMT2AMCL1NPC1 | |
| SCHEMBL30073941 | 0.78 | KMT2A (0.54) | HPGDMAPTKMT2AMCL1NPC1 | |
| SCHEMBL25214710 | 0.74 | HPGD (0.85) | HPGDMAPTKMT2AMCL1NPC1 | |
| SCHEMBL25201168 | 0.74 | HPGD (0.85) | HPGDMAPTKMT2AMCL1NPC1 | |
| SCHEMBL7506884 | 0.72 | ITGB3 (0.66) | ITGB3ITGAVITGA2BITGB1ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | claimed |
| EP-0894084-B1 | CINNAMIC ACID DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | SEARLE & CO (US) | 2002-06-26 | — | — | EP | disclosed |