Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8056613 | 0.73 | KDM4E (0.31) | KDM4E | |
| SCHEMBL7971936 | 0.73 | KDM4E (0.33) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL8052680 | 0.72 | CHEK1 (0.30) | CHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL8053661 | 0.72 | CHEK1 (0.30) | CHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL8054632 | 0.72 | KDM4E (0.35) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL5044459 | 0.69 | — | — | |
| SCHEMBL8053799 | 0.69 | SSTR4 (0.33) | CHEK1LIMK1DYRK1ACLK4KDM4E | |
| SCHEMBL8056659 | 0.69 | — | — | |
| SCHEMBL8059116 | 0.67 | ELANE (0.33) | KDM4E | |
| SCHEMBL7632455 | 0.67 | DYRK1A (0.39) | CHEK1LIMK1DYRK1ACLK4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760370-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5990101-A | Carbapenem derivatives | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0760370-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-03-05 | — | — | EP | disclosed |