Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054632 | 0.79 | KDM4E (0.35) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL8053799 | 0.76 | SSTR4 (0.33) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL8056613 | 0.71 | KDM4E (0.31) | KDM4E | |
| SCHEMBL7963870 | 0.70 | CHEK1 (0.31) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL8059116 | 0.69 | ELANE (0.33) | KDM4E | |
| SCHEMBL8052680 | 0.68 | CHEK1 (0.30) | CHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL7632455 | 0.61 | DYRK1A (0.39) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL5044459 | 0.60 | — | — | |
| SCHEMBL8054483 | 0.58 | HPGD (0.40) | KDM4ECHEK1LIMK1DYRK1ACLK4 | |
| SCHEMBL27567869 | 0.56 | HRH4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242437-B1 | HAS HIGHER ANTIMICROBIAL ACTIVITY AGAINST METHICILLINE-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA), PENICILLIN-RESISTANT STREPTOCOCCUS PNEUMONIAE (PRSP), AND IMIPENEM-RESISTANT PSEUDOMONAS AERUGINOSA ONIUM SALT | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0947517-A1 | CEPHEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |