Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 6/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750224 | 0.87 | KMT2A (0.47) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL12098650 | 0.83 | UCHL1 (0.52) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL3835668 | 0.82 | USP30 (0.55) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL3830118 | 0.81 | UCHL1 (0.49) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL3833756 | 0.81 | UCHL1 (0.49) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL3835396 | 0.79 | NPC1 (0.48) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL571212 | 0.78 | UCHL1 (0.46) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL2072192 | 0.76 | USP30 (0.54) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL3448503 | 0.75 | UCHL1 (0.43) | UCHL1USP30NPC1LMNANPSR1 | |
| SCHEMBL14037470 | 0.75 | NPC1 (0.58) | UCHL1USP30NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |