Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 2/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750225 | 0.89 | KMT2A (0.53) | USP30NPC1MCL1LMNANPSR1 | |
| SCHEMBL2075346 | 0.88 | VHL (0.49) | NPC1OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL2075347 | 0.88 | VHL (0.49) | NPC1OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL2076012 | 0.86 | VHL (0.46) | USP30NPC1OPRM1OPRD1OPRK1 | |
| SCHEMBL2076014 | 0.86 | VHL (0.46) | USP30NPC1OPRM1OPRD1OPRK1 | |
| SCHEMBL2074630 | 0.84 | VHL (0.53) | OPRM1OPRD1OPRK1MCL1KMT2A | |
| SCHEMBL2074631 | 0.84 | VHL (0.53) | OPRM1OPRD1OPRK1MCL1KMT2A | |
| SCHEMBL7858495 | 0.82 | VHL (0.51) | MCL1KMT2AMEN1VHL | |
| SCHEMBL3165695 | 0.82 | CMA1 (0.63) | KMT2AMEN1ALDH1A1ACECMA1 | |
| SCHEMBL21748404 | 0.82 | CMA1 (0.63) | KMT2AMEN1ALDH1A1ACECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |