Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MC3R | P41968 | 2/20 | 0.36 |
| ▸ | MC1R | Q01726 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447108 | 1.00 | MEN1 (0.39) | MEN1NPC1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7453049 | 0.92 | ROCK2 (0.37) | SLC6A4HRH3ROCK2DPP4 | |
| SCHEMBL7486269 | 0.92 | ROCK2 (0.37) | SLC6A4HRH3ROCK2DPP4 | |
| SCHEMBL7485095 | 0.90 | SLC6A4 (0.39) | MEN1NPC1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7485089 | 0.90 | SLC6A4 (0.39) | MEN1NPC1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7489629 | 0.89 | SLC6A4 (0.38) | MEN1NPC1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7489622 | 0.89 | SLC6A4 (0.38) | MEN1NPC1RAB9AKMT2ASLC6A4 | |
| SCHEMBL7490466 | 0.88 | HRH3 (0.37) | SLC6A4HRH3DPP4CCR9 | |
| SCHEMBL7490459 | 0.88 | HRH3 (0.37) | SLC6A4HRH3DPP4CCR9 | |
| SCHEMBL7452435 | 0.87 | SLC6A4 (0.38) | KMT2ASLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |