SCHEMBL7496071

SCHEMBL7496071

O=C(Nc1ccccc1)Nc1ccccc1CCN1CCC(Cc2ccccc2)CC1

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 17/20 0.80
FAAH O00519 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6703659 0.88 CCR3 (1.00) CCR3
SCHEMBL7506409 0.82 FAAH (0.60) CCR3FAAH
SCHEMBL6705360 0.81 CCR3 (1.00) CCR3
SCHEMBL6704121 0.79 CCR3 (0.79) CCR3
SCHEMBL6339130 0.79 CCR3 (1.00) CCR3
SCHEMBL6700148 0.79 CCR3 (1.00) CCR3
SCHEMBL7500974 0.79 CCR3 (0.84) CCR3
SCHEMBL6330827 0.78 CCR3 (0.93) CCR3
SCHEMBL6703651 0.78 CCR3 (0.82) CCR3
Hydrochloric Acid SCHEMBL7500878 0.78 CCR3 (0.83) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140087-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 EP disclosed
EP-1140087-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-10-10 EP disclosed
WO-2000035454-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO disclosed