Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11200015 | 0.98 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| Hydrochloric Acid SCHEMBL11195226 | 0.98 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| SCHEMBL11498275 | 0.90 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| Hydrochloric Acid SCHEMBL11198045 | 0.89 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| SCHEMBL11195148 | 0.87 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| SCHEMBL6162106 | 0.87 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| Bromide SCHEMBL11196546 | 0.86 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| SCHEMBL11463949 | 0.84 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| Hydrochloric Acid SCHEMBL11198129 | 0.82 | HTR2C (0.55) | SLC6A2SLC6A4SLC6A3HTR1AHRH1 | |
| SCHEMBL49168 | 0.82 | PTGDR2 (0.44) | SLC6A2SLC6A4SLC6A3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241071-A | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes | AMERICAN HOECHST CORPORATION (US) | 1980-12-23 | — | — | US | claimed |
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2020-11-12 | — | — | US | disclosed |
| WO-2019115586-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-06-20 | — | — | WO | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235538-B2 | Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| EP-1171122-A4 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1171122-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |
| WO-2000059502-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200352931-A1 | OXALAMIDES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | SLC6A2 1396/4885SLC6A4 876/4885SLC6A3 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.