⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7492173 | 0.84 | — | — | |
| SCHEMBL7499385 | 0.82 | SERPINE1 (0.46) | — | |
| SCHEMBL7492996 | 0.81 | — | — | |
| SCHEMBL7498059 | 0.81 | THRB (0.40) | — | |
| SCHEMBL7494301 | 0.81 | MDM2 (0.38) | — | |
| SCHEMBL7496736 | 0.79 | — | — | |
| SCHEMBL7497206 | 0.77 | — | — | |
| SCHEMBL7496311 | 0.77 | — | — | |
| SCHEMBL7496652 | 0.77 | CYP19A1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL7497423 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | claimed |
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |