Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497627 | 1.00 | BRD4 (0.55) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7497359 | 0.87 | ALDH1A1 (0.53) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7497354 | 0.87 | ALDH1A1 (0.53) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7502533 | 0.87 | ALDH1A1 (0.48) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7502537 | 0.87 | ALDH1A1 (0.48) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7498069 | 0.86 | ALDH1A1 (0.56) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7498239 | 0.86 | ALDH1A1 (0.52) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7500262 | 0.86 | ALDH1A1 (0.52) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7501263 | 0.86 | ALDH1A1 (0.52) | BRD4ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7495825 | 0.86 | ALDH1A1 (0.52) | BRD4ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757681-B1 | CONDENSED HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE AS GnRH ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-09-18 | — | — | EP | disclosed |