Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497746 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRPDE4BPDE4DFKBP1A | |
| SCHEMBL7497742 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRPDE4BPDE4DFKBP1A | |
| SCHEMBL7505856 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRPDE4BPDE4DFKBP1A | |
| SCHEMBL7502547 | 0.90 | GLA (0.48) | SMN1; SMN2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL7504683 | 0.88 | PDE4B (0.49) | TSHRPDE4BPDE4DLMNAALDH1A1 | |
| SCHEMBL7495012 | 0.87 | PDE4B (0.46) | SMN1; SMN2TSHRPDE4BPDE4DLMNA | |
| SCHEMBL7496362 | 0.79 | POLB (0.55) | SMN1; SMN2TSHRFKBP1ALMNAALDH1A1 | |
| SCHEMBL7499394 | 0.72 | PDE4B (0.50) | SMN1; SMN2TSHRPDE4BPDE4DLMNA | |
| SCHEMBL7507216 | 0.70 | PDE4B (0.46) | SMN1; SMN2TSHRPDE4BPDE4DLMNA | |
| SCHEMBL7500578 | 0.67 | KMT2A (0.51) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5972946-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0826673-A1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1998-03-04 | — | — | EP | disclosed |