Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.46 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504683 | 0.88 | PDE4B (0.49) | PDE4BPDE4DUSP1WDR48RXRA | |
| SCHEMBL7497748 | 0.87 | SMN1; SMN2 (0.49) | PDE4BPDE4DTSHRALDH1A1LMNA | |
| SCHEMBL7497746 | 0.87 | SMN1; SMN2 (0.49) | PDE4BPDE4DTSHRALDH1A1LMNA | |
| SCHEMBL7505856 | 0.87 | SMN1; SMN2 (0.49) | PDE4BPDE4DTSHRALDH1A1LMNA | |
| SCHEMBL7497742 | 0.87 | SMN1; SMN2 (0.49) | PDE4BPDE4DTSHRALDH1A1LMNA | |
| SCHEMBL7502547 | 0.77 | GLA (0.48) | RXRANR4A2TSHRALDH1A1KDM4E | |
| SCHEMBL7507216 | 0.70 | PDE4B (0.46) | PDE4BPDE4DTSHRALDH1A1KDM4E | |
| SCHEMBL7499394 | 0.70 | PDE4B (0.50) | PDE4BPDE4DRXRANR4A2TSHR | |
| SCHEMBL7500902 | 0.69 | GHSR (0.39) | LMNA | |
| SCHEMBL7500897 | 0.69 | GHSR (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826673-B1 | ACETAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2002-11-20 | — | — | EP | disclosed |