Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643035 | 1.00 | GLA (0.62) | GLAPOLBL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL12641073 | 0.91 | POLB (0.53) | GLAPOLBL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL3545687 | 0.83 | GLA (0.57) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL7093218 | 0.83 | GLA (0.57) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL4518744 | 0.79 | GLA (0.53) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL4518742 | 0.79 | GLA (0.53) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL5103440 | 0.77 | TSHR (0.53) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL5109358 | 0.75 | GLA (0.55) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL5921835 | 0.75 | GLA (0.55) | GLAL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL932446 | 0.75 | POLB (0.53) | POLBSMN1; SMN2LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187828-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000078748-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-28 | — | — | WO | disclosed |