Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545687 | 1.00 | GLA (0.57) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL643035 | 0.83 | GLA (0.62) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL7498041 | 0.83 | GLA (0.62) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL4518744 | 0.82 | GLA (0.53) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL4518742 | 0.82 | GLA (0.53) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5921835 | 0.78 | GLA (0.55) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5109358 | 0.78 | GLA (0.55) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL3547552 | 0.77 | LMNA (0.50) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL5103440 | 0.76 | TSHR (0.53) | GLALMNASMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9021160 | 0.75 | GAA (0.43) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165488-B1 | PROCESS FOR THE PREPARATION OF POLYAMINO SUCCINIC ACIDS AND DERIVATIVES THEREOF | DOW CHEMICAL CO (US) | 2003-08-13 | — | — | EP | disclosed |
| US-6465690-B1 | Process for the preparation of polyamino succinic acids and derivatives thereof | THE DOW CHEMICAL COMPANY | 2002-10-15 | — | — | US | disclosed |