SCHEMBL7498115

SCHEMBL7498115

CON=C(C=NOC(C)c1ccccc1C(=NOC)C(=O)OC)c1ccc(F)cc1C

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.36
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6704054 0.92 HIF1A (0.36) HIF1A
SCHEMBL7542494 0.91 NPC1 (0.30) NPC1POLBRAB9AKMT2A
SCHEMBL7492778 0.87 HIF1A (0.36) HIF1A
SCHEMBL7742093 0.86 HIF1A (0.42) HIF1A
SCHEMBL7504420 0.85 HIF1A (0.38) HIF1ANPC1RAB9AKMT2A
SCHEMBL7494764 0.84 HIF1A (0.40) HIF1A
SCHEMBL8615822 0.84 MAPK14 (0.33) NPC1POLBRAB9AKMT2A
SCHEMBL7784487 0.83 RECQL (0.32)
SCHEMBL7502694 0.83 HIF1A (0.42) HIF1A
SCHEMBL7130516 0.81 HIF1A (0.42) HIF1ANPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420423-B1 PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH BAYER AKTIENGESELLSCHAFT (DE) 2002-07-16 US disclosed
EP-1207152-A2 Pesticides Bayer Aktiengesellschaft (DE) 2002-05-22 EP disclosed
US-5985921-A OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS NOVARTIS CORPORATION (US) 1999-11-16 US disclosed
EP-0865424-A1 PESTICIDES Novartis AG (CH) 1998-09-23 EP disclosed
WO-1997020809-A1 PESTICIDES NOVARTIS AG (CH) 1997-06-12 WO disclosed