Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522437 | 0.86 | GRIN2D (0.44) | CCR4TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL2071403 | 0.85 | GRIN2D (0.44) | HTR7HTR1ADRD2HTR2ATSHR | |
| SCHEMBL14821457 | 0.81 | GRIN2D (0.39) | CCR4DRD2HTR2ATSHRKDM4E | |
| SCHEMBL15850967 | 0.80 | GRIN2D (0.41) | CCR4TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL5846680 | 0.80 | HTR7 (0.47) | HTR7HTR1ADRD2HTR2ATSHR | |
| SCHEMBL29786265 | 0.80 | HTR7 (0.47) | HTR7HTR1ADRD2HTR2ATSHR | |
| SCHEMBL12660023 | 0.78 | CCR1 (0.41) | CCR4ALDH1A1HRH3GRIN2DGRIN3B | |
| SCHEMBL2234375 | 0.78 | GRIN2D (0.44) | CCR4DRD2HTR2ATSHRKDM4E | |
| SCHEMBL20892198 | 0.78 | CCR4 (0.37) | CCR4TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL906702 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096893-A | Process and intermediates for 3-heteroaryl-4(3H) quinazolines | PFIZER INC. (US) | 2000-08-01 | — | — | US | claimed |
| EP-0763033-B1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2002-10-16 | — | — | EP | disclosed |
| US-6096893-A | Process and intermediates for 3-heteroaryl-4(3H) quinazolines | PFIZER INC. (US) | 2000-08-01 | — | — | US | disclosed |
| US-5665738-A | HYPOTENSIVE AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-09-09 | — | — | US | disclosed |
| EP-0763033-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032198-A1 | IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-11-30 | — | — | WO | disclosed |