⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7497099 | 0.86 | MAPT (0.42) | — | |
| SCHEMBL1158791 | 0.82 | TDP1 (0.40) | — | |
| SCHEMBL1706412 | 0.80 | — | — | |
| SCHEMBL1031232 | 0.79 | — | — | |
| SCHEMBL3844294 | 0.78 | — | — | |
| SCHEMBL4267168 | 0.78 | — | — | |
| SCHEMBL5196980 | 0.75 | CHRM1 (0.34) | — | |
| SCHEMBL7204354 | 0.75 | CHRM1 (0.34) | — | |
| SCHEMBL20490045 | 0.74 | CHRM1 (0.42) | — | |
| SCHEMBL276025 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799830-B1 | Imidazothiazol derivatives as components of liquid crystalline mixtures | ROLIC AG (CH) | 2002-05-29 | — | — | EP | disclosed |
| US-5851425-A | Imidazothiazoles | ROLIC AG (CH) | 1998-12-22 | — | — | US | disclosed |
| EP-0799830-A1 | Imidazothiazol derivatives as components of liquid crystalline mixtures | Rolic AG (CH) | 1997-10-08 | — | — | EP | disclosed |
| EP-0269963-B1 | Ferroelectric liquid crystals | HOFFMANN LA ROCHE (CH) | 1995-02-22 | — | — | EP | disclosed |
| US-5100577-A | FERROELECTRIC LIQUID CRYSTAL MIXTURES AND COMPOUNDS AS WELL AS ELECTRO-OPTICAL DEVICES EMPLOYING SAME | HOFFMAN-LA ROCHE INC. (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0269963-A2 | Ferroelectric liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1988-06-08 | — | — | EP | disclosed |