Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1158791 | 0.77 | TDP1 (0.40) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL2590996 | 0.76 | GPR84 (0.41) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL7498237 | 0.75 | — | — | |
| SCHEMBL1706412 | 0.75 | — | — | |
| SCHEMBL4267168 | 0.73 | — | — | |
| SCHEMBL3844294 | 0.73 | — | — | |
| SCHEMBL11507023 | 0.72 | — | — | |
| SCHEMBL27813853 | 0.71 | ELANE (0.44) | TDP1ALDH1A1MAPT | |
| SCHEMBL7181549 | 0.71 | CA2 (0.46) | TDP1CYP3A4TSHRHPGDMAPT | |
| SCHEMBL5196980 | 0.70 | CHRM1 (0.34) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1342110-A2 | OPTICAL WAVEGUIDES AND METHODS FOR MAKING THE SAME | Goodrich Corporation (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002010810-A2 | OPTICAL WAVEGUIDES AND METHODS FOR MAKING THE SAME | GOODRICH CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |