Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 6/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895877 | 0.92 | ADRB2 (0.36) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL12673661 | 0.87 | KCNH2 (0.41) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL12665504 | 0.86 | KCNH2 (0.43) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL2898552 | 0.86 | KCNH2 (0.40) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL2898551 | 0.86 | KCNH2 (0.40) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL7497106 | 0.84 | GSK3B (0.41) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| SCHEMBL16518636 | 0.82 | KCNH2 (0.42) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| Garenoxacin SCHEMBL13575803 | 0.81 | KCNH2 (0.42) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| Garenoxacin SCHEMBL2103727 | 0.81 | KCNH2 (0.42) | KDM4EHPGDKCNH2GSK3BTOP2A | |
| Garenoxacin SCHEMBL29870066 | 0.81 | KCNH2 (0.42) | KDM4EHPGDKCNH2GSK3BTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882725-B1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6025370-A | METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0882725-A1 | QUINOLONECARBOXYLIC ACID DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |