Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR3 | O60755 | 2/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PTAFR | P25105 | 2/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049974 | 0.89 | GALR3 (0.50) | GALR3NR2F2TNFRAB9APTAFR | |
| Bromide SCHEMBL9054549 | 0.87 | GALR3 (0.49) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL9051522 | 0.86 | GALR3 (0.52) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL9051695 | 0.86 | GALR3 (0.50) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL7497522 | 0.86 | GALR3 (0.68) | GALR3NR2F2TNFRAB9APTAFR | |
| Bromide SCHEMBL9052476 | 0.84 | GALR3 (0.51) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL9057251 | 0.83 | PTAFR (0.48) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL9051019 | 0.83 | PTAFR (0.49) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL7494477 | 0.83 | GALR3 (0.48) | GALR3NR2F2TNFRAB9APTAFR | |
| SCHEMBL8324796 | 0.83 | PTAFR (0.56) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734386-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LAB (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-0734386-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | Abbott Laboratories (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5486525-A | ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1995016687-A1 | PLATELET ACTIVATING FACTOR ANTAGONISTS: IMIDAZOPYRIDINE INDOLES | ABBOTT LABORATORIES (US) | 1995-06-22 | — | — | WO | disclosed |